Application de l’activité antiurolithiasique de certains extraits d'une plante médicinale

Abstract

The field of herbal medicine is widespread in our time and opens up new treatment horizons. We set out in this work with the aim of evaluating the effectiveness of medicinal plants that have an effect on kidney stones (nephrolithiasis). Through people's experiences, we came to choose the Periploca laevigata plant and study its effect on kidney stones. On the other hand, and to enhance our research, we decided to compare the effectiveness of this plant with Renalof, which is known to affect stones. To further support our research, we chose a plant that is able to contribute to increasing the formation of Stones We found Spinacia oleracea plant because it contains the basic element for the formation of "calcium oxalate". Periploca laevigata plant contains tannins, alkaloids, saponins, reducing compounds, sterols, and triterpenes, and a high percentage of flanoids estimated at 28.17 ± 0.464 mg EAG/g MS compared to nonphenols, which was estimated at 12.02 ± 0.15 mg EAG/g MS. Spinacia oleracea plant contains alkaloids, reducing compound, sterols, and triterpenes, and a high percentage of flavonoids estimated at 25.6 ± 0.068 mg EQ/g MS, compared to nonphenols, which was estimated at 5.9 ± 0.422 mg EQ/g MS. Based on the results of our stone formation inhibition study, we concluded that the drug Renalof inhibited stone formation by 69% and the plant Periploca laevigata by 26,76%. At the end of the study, we concluded that the 'Hellab', Periploca laevigata, had a positive effect on kidney stones.